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KMID : 0356620110260040345
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Journal of Korean Society of Endocrinology
2011 Volume.26 No. 4 p.345 ~ p.347
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Hyperprolactinemia-Associated Breast Uptake of Radioiodine Following 131I Postablation Scan in Differentiated Thyroid Cancer
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Ahn Jae-Hee
Kim Sun-Youn
Kim Ye-Ji
Lee Suk-Young
Lee Jae-Hyoung
Kang Seung-Hun
Hong Ho-Cheol
Yang Sae-Jeong
Yoo Hye-Jin
Seo Ji-A
Kim Sin-Gon
Kim Nan-Hee
Choi Kyung-Mook
Baik Sei-Hyun
Choi Dong-Seop
Choi Hae-Yoon
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Abstract
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Scanning with whole-body 131I scintigraphy after surgery has been a valuable diagnostic modality in the surveillance of patients with differentiated thyroid cancer. Radioiodine uptake is rarely observed in non-lactating breast tissue, which mimics thyroid cancer metastasis. We now report a case of a 45-year-old female thyroid cancer patient who underwent radioiodine therapy, and in whom breast uptake of radioiodine was observed on a post-therapy whole body scan. Her serum prolactin level was elevated to 328 ng/mL at the time of the radioiodine uptake, and the hyperprolactinemia was induced by her antipsychotic medications. Six months after she discontinued that medication, her serum prolactin level was normalized to 12.6 ng/mL and breast uptake of iodine was no longer present in a follow-up whole body scan.
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KEYWORD
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Antipsychotic agents, Differentiated thyroid cancer, Hyperprolactinemia
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